主演男優賞（コメディ部門）

This is a list of winners and nominees of the Primetime Emmy Award for Outstanding Lead Actor in a Comedy Series. The award is presented to the best performance by a lead actor in a television comedy series. Beginning with 1966, leading actors in comedy have competed alone. However, these comedic performances included actors from miniseries, telefilms, and guest performers competing against main cast competitors. Such instances are marked below:# – Indicates a performance in a miniseries or television film, prior to the category's creation § – Indicates a performance as a guest performer, prio