In 2000, Barclay joined forces with fellow NYPD Blue producers Steven Bochco and Nicholas Wootton to create City of Angels, a medical drama with a predominantly African-American cast including Blair Underwood, Viola Davis, Octavia Spencer, Maya Rudolph, and Vivica Fox. The show aired on CBS for two seasons while winning two NAACP awards.
In 2002 he returned to the John Wells fold to produce and direct a pilot, The Big Time, featuring Christina Hendricks, Dylan Baker, Molly Ringwald and Christopher Lloyd—which eventually aired as a two-hour movie. In the years that followed, Barclay worked on a wide variety of television dramas and comedies. He served as co-executive producer and producing director of the series Cold Case, for which he has also directed nine episodes. Other shows he directed in the decade include The West Wing, Huff, Law & Order, Numb3rs, Lost, House, The Shield, Weeds, Monk,The Good Wife, NCIS: Los Angeles, Sons of Anarchy, CSI, The Mentalist and 9 episodes of Glee.
2008 marked Barclay's return to HBO, where he executive produced three seasons of In Treatment, as well as directed 36 episodes. The series garnered a Golden Globes nomination for Best Drama Series in 2009 and series lead Gabriel Byrne won the Golden Globe for Best Television Actor in a Drama Series that same year. In 2008, the series won 2 Emmys for Glynn Turman for Outstanding Guest Actor in a Drama Series and Dianne Wiest won for Outstanding Supporting Actress in a Drama Series.
