His early works include a portrait of Mahatma Gandhi made from iron nails, taking three years to complete. He has also created portraits of figures like Dhirubhai Ambani, Jesus, Mary, Sai Baba, and Mohammed bin Rashid Al Maktoum using the same technique.
In 2013, he created a monumental wall installation titled Champa, depicting a horse and a jockey. The artwork was constructed using spare parts from various automobiles and took over eight months to complete.
In 2014, Khan created an installation work depicting a crying girl child made from medical equipment associated with sex-selective abortion. This piece was part of Save the girl child campaign.
Wajid Khan also created a portrait of Sri Lankan architect Geoffrey Bawa using stones of various sizes and shapes. The stones were arranged on a metal sheet, secured with glue. The process involved the use of tools such as tongs and tweezers to form an outline of Bawa's face.
In 2016, Wajid Khan produced a series of artworks using spoons and forks to depict various life stages, including maternal themes, dance, and birds. His spoon art employs everyday utensils as mediums for artistic expression.
In 2018, Khan created a 2.5-foot by 2.5-foot installation of Vallabhbhai Patel using parts from a car and motorcycle engine, forming a portrait of Sardar Patel through shadow art techniques. This piece was installed at Bharat Bhavan, a public multi-arts museum in Bhopal. Later that year, he was commissioned to create a 170-foot statue of Swami Vivekananda from a combination of eight metals, which was reported to be the tallest statue of Swami Vivekanand in India.
On 2 October 2019, marking Mahatma Gandhi's 150th birth anniversary, Wajid Khan collaborated with the Plastic Donation Center to create a human mosaic of Gandhi at TT Nagar Stadium, Bhopal. The artwork, involving the participation of 6,000 schoolchildren, was designed to raise awareness about plastic pollution. The event was attended by officials, including Jitendra Patwari, Cabinet Minister for Higher Education, and Alok Sharma, Mayor of Bhopal.
Khan made a 12×8 feet portrait of poet Ghalib using wine glasses, bottles, and jugs, which was showcased at the Urdu literary festival Jashn-e-Rekhta in December 2019. In 2020, he created a 40-foot hydra-like kinetic art installation made of 300 steel bowls that locked and unlocked with the wind. The artwork depicts 's societal unity, where the removal of a single bowl disrupts the balance. The installation was exhibited at the Namaste Orchha Festival, organized by the Madhya Pradesh Tourism Board, in March 2020.